Keywords
Citation
(2011), "Cognitive Impairment and Dementia in Parkinson’s Disease", International Journal of Health Care Quality Assurance, Vol. 24 No. 3. https://doi.org/10.1108/ijhcqa.2011.06224cae.003
Publisher
:Emerald Group Publishing Limited
Copyright © 2011, Emerald Group Publishing Limited
Cognitive Impairment and Dementia in Parkinson’s Disease
Cognitive Impairment and Dementia in Parkinson’s Disease
Article Type: Recent publications From: International Journal of Health Care Quality Assurance, Volume 24, Issue 3
Edited by Murat Emre,OUP,2010,ISBN10: 978-0-19-956411-8
Keywords: Parkinson’s disease health implications, Effective treatment and therapy, Dementia research and practice
Parkinson’s disease has long been perceived as a pure motor disorder, partly due to its initial description by James Parkinson, who suggested that “senses and intellect remain intact”, and partly due to the fact that patients with PD did not survive long, before effective treatment became available. As the survival time of patients with Parkinson’s disease has substantially increased due to modern treatment, it has become apparent that cognitive deficits and dementia are also frequent features, especially in elderly patients. With the progression of the disease and age, dementia develops in a substantial number of patients and constitutes a major therapeutic challenge. Dementia has thus increasingly been the focus of research and practice in recent years and a large body of knowledge has been accumulated. Despite these developments there has been no single volume dedicated to this topic.
This book provides an extensive overview of the current status of knowledge pertaining to cognitive impairment and dementia associated with Parkinson’s disease, intended as a reference book for general neurologists, neurology residents and also those with a special interest in movement disorders. In this edited volume experts in the field describe in detail all aspects of cognitive impairment and dementia in Parkinson’s disease, including epidemiology, spectrum of clinical features, pathology, neurochemistry and genetics, findings in auxiliary investigations, relation to other neurodegenerative disorders, diagnostic process and management, and rounded up by discussion of future research directions and expectations. The text is complemented and enriched with tables, figures and heavily referenced to encompass all relevant literature.
Contents include:
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Introduction.
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The epidemiology of dementia associated with Parkinson’s disease.
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General features, mode of onset and the course of dementia in Parkinson’s disease.
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Cognitive profile in Parkinson’s disease dementia.
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Neuropsychiatric symptoms in Parkinson’s disease dementia.
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The interaction between affect and executive functions in Parkinson’s disease.
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Motor symptoms and phenotype in patients with Parkinson’s disease dementia.
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Interaction between cognition and gait in patients with Parkinson’s disease.
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Disorders of sleep and autonomic function in Parkinson’s disease dementia.
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Neuroimaging in Parkinsons’ disease dementia.
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Electrophysiological and other auxiliary investigations in patients with Parkinson’s disease dementia.
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The genetic basis of dementia in Parkinson’s disease.
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Neurochemical pathology of Parkinson’s disease dementia.
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Pathological correlates of dementia in Parkinson’s disease.
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Cognitive impairment in non-demented patients with Parkinson’s disease.
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Spectrum of lewy body dementias: relationship of PD-D to DLB.
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Spectrum of disorders with Parkinsonism and dementia.
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Diagnosis of dementia in Parkinson’s disease.
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Management of Parkinson’s disease dementia and dementia with lewy bodies.
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Parkinson’s disease: what will the future bring?