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Markers of the progression of kidney damage analyzed by soft computing approach

Danijela Tasic (Clinic of Nephrology, Clinical Center Nis, Nis, Serbia and Faculty of Medicine, University of Nis, Nis, Serbia)

Sensor Review

ISSN: 0260-2288

Article publication date: 1 December 2017

Issue publication date: 8 January 2018

84

Abstract

Purpose

The purpose of this study is to analyze markers of the progression of kidney damage by a soft computing approach.

Design/methodology/approach

Because markers of the progression of kidney damage, namely, plasminogen activator inhibitor-1 (PAI-1), interleukin-8 (IL-8) and highly sensitive troponin T (cTnhsT), are complex parameters, a soft computing approach was used for the assessment of functional glomerular reserves, through the use of the Modification of the Diet in Renal Disease (MDRD) formula based on serum creatinine and EPI creatinine-cystatin C formula (chronic kidney disease epidemiology collaboration).

Findings

The soft computing approach was used to detect which factors (PAI-1, IL-8 and cTnhsT) are the most important for the MDRD formula based on serum creatinine or the EPI creatinine–cystatin C formula.

Originality/value

Markers of the progression of kidney damage were analyzed by the soft computing approach.

Keywords

Citation

Tasic, D. (2018), "Markers of the progression of kidney damage analyzed by soft computing approach", Sensor Review, Vol. 38 No. 1, pp. 74-78. https://doi.org/10.1108/SR-06-2017-0118

Publisher

:

Emerald Publishing Limited

Copyright © 2018, Emerald Publishing Limited

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