Electrochemical DNA biosensors: a review
ISSN: 0260-2288
Article publication date: 4 April 2018
Issue publication date: 24 January 2019
Abstract
Purpose
This review aims to focus on recent reported research work on the construction and function of different electrochemical DNA biosensors. It also describes different sensing materials, chemistries of immobilization probes, conditions of hybridization and principles of transducing and amplification strategies.
Design/methodology/approach
The human disease-related mutated genes or DNA sequence detection at low cost can be verified by the electrochemical-based biosensor. A range of different chemistries is used by the DNA-based electrochemical biosensors, out of which the interactions of nanoscale material with recognition layer and a solid electrode surface are most interesting. A diversity of advancements has been made in the field of electrochemical detection.
Findings
Some important aspects are also highlighted in this review, which can contribute in the creation of successful biosensing devices in the future.
Originality/value
This paper provides an updated review of construction and sensing technologies in the field of biosensing.
Keywords
Acknowledgements
Conflict of Interest: The authors declare that there is no conflict of interest related to this article.
Citation
Rafique, B., Iqbal, M., Mehmood, T. and Shaheen, M.A. (2019), "Electrochemical DNA biosensors: a review", Sensor Review, Vol. 39 No. 1, pp. 34-50. https://doi.org/10.1108/SR-08-2017-0156
Publisher
:Emerald Publishing Limited
Copyright © 2018, Emerald Publishing Limited