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Sensitivity studies and optimization of arrangements of optically pumped magnetometers in simulated magnetoencephalography

Roland Eichardt (Insitute of Biomedical Engineering and Informatics, Technische Universität Ilmenau, Ilmenau, Germany)
Daniel Strohmeier (Insitute of Biomedical Engineering and Informatics, Technische Universität Ilmenau, Ilmenau, Germany)
Alexander Hunold (Insitute of Biomedical Engineering and Informatics, Technische Universität Ilmenau, Ilmenau, Germany)
René Machts (Insitute of Biomedical Engineering and Informatics, Technische Universität Ilmenau, Ilmenau, Germany)
Jens Haueisen (Insitute of Biomedical Engineering and Informatics, Technische Universität Ilmenau, Ilmenau, Germany)
Gregor Oelsner (Magnetometry Research Group, Leibniz Institute of Photonic Technology, Jena, Germany)
Christian B. Schmidt (Magnetometry Research Group, Leibniz Institute of Photonic Technology, Jena, Germany)
Volkmar Schultze (Magnetometry Research Group, Leibniz Institute of Photonic Technology, Jena, Germany)
Ronny Stolz (Magnetometry Research Group, Leibniz Institute of Photonic Technology, Jena, Germany)
Uwe Graichen (Institute of Biomedical Engineering and Informatics, Technische Universität Ilmenau, Ilmenau, Germany)

COMPEL - The international journal for computation and mathematics in electrical and electronic engineering

ISSN: 0332-1649

Article publication date: 18 March 2019

Issue publication date: 3 June 2019

152

Abstract

Purpose

The purpose of this paper is to present a simulation study using a model of a new optically pumped magnetometer sensor for application in the field of magnetoencephalography. The effects of sensor distance and orientation on the measurement information and the sensitivity to neuronal sources are investigated. Further, this paper uses a combinatorial optimization approach for sensor placement to measure spontaneous activity in the region of the occipital cortex.

Design/methodology/approach

This paper studies the effects of sensor distance and orientation on sensitivity to cortical sources and measurement information. A three-compartment model of the head, using the boundary element method, is applied. For sensor setup optimization, a combinatorial optimization scheme is developed.

Findings

The sensor distance to sources considerably affects the sensitivity and the retrieved information. A specific arrangement of four sensors for measuring spontaneous activity over the occipital part of the head is optimized by effectively avoiding position conflicts.

Research limitations/implications

Individual head models, as well as more detailed noise and signal models, will increase the significance for specific-use cases in future studies.

Originality/value

Effects of sensor distance and orientation are specifically evaluated for a new optically pumped magnetometer. A discrete optimization scheme for sensor optimization is introduced. The presented methodology is applicable for other sensor characterization and optimization problems. The findings contribute significantly to the development of new sensors.

Keywords

Acknowledgements

This work was supported by the Free State of Thuringia and the European Social Fund (2015FGR0085), and by the German Research Foundation (Ha 2899/21-1).

Citation

Eichardt, R., Strohmeier, D., Hunold, A., Machts, R., Haueisen, J., Oelsner, G., Schmidt, C.B., Schultze, V., Stolz, R. and Graichen, U. (2019), "Sensitivity studies and optimization of arrangements of optically pumped magnetometers in simulated magnetoencephalography", COMPEL - The international journal for computation and mathematics in electrical and electronic engineering, Vol. 38 No. 3, pp. 953-964. https://doi.org/10.1108/COMPEL-09-2018-0372

Publisher

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Emerald Publishing Limited

Copyright © 2019, Emerald Publishing Limited

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